Grove Lab

Grove Lab

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We are focusing on how proteins bind to DNA to control cellular function, including processes such as DNA repair, gene expression, and bacterial virulence.

Our research focuses on both prokaryotic and eukaryotic proteins that change DNA packing to regulate events such as gene expression and DNA repair. We focus on the eukaryotic HMGB proteins and bacterial HU and Dps. Another main focus is on bacterial transcription factors that belong to the MarR family and their roles in stress responses and virulence.

The transcription factor CwiR is important for envelope integrity in Burkholderia thailandensis - BMC Microbiology 10/23/2026

The latest from Sarmin and Ahmed - characterization of a B. thailandensis transcription factor that is important for antibiotic resistance:

The transcription factor CwiR is important for envelope integrity in Burkholderia thailandensis - BMC Microbiology Background The bacterial cell envelope, particularly the outer membrane of Gram-negative species, is essential for survival and intrinsic resistance to antibiotics. However, the regulatory mechanisms that maintain envelope integrity have only been partially elucidated. Members of the genus Burkholde...

The Agrobacterium fabrum efflux pump PecM serves as a critical metabolic relief valve to maintain cellular homeostasis | mSphere 10/10/2026

The latest from Arpita and Ahmed on the importance of efflux pumps!

The Agrobacterium fabrum efflux pump PecM serves as a critical metabolic relief valve to maintain cellular homeostasis | mSphere Efflux pumps often receive attention in the context of protecting bacteria from environmental toxins such as antibiotics. However, they are also important for exporting metabolic intermediates that may otherwise disrupt cellular processes. Bacterial metabolism of aromatic compounds can generate 4-hy...

Modest Changes in Extracellular Impose Metabolic and Envelope Remodeling in 09/30/2026

Congrats to Ahmed and Sarmin!
Their paper showing what happens to B. thailandensis when it encounters a different pH in the environment has appeared online:

Modest Changes in Extracellular Impose Metabolic and Envelope Remodeling in Using quantitative proteomics and transcriptomics, we characterized the response of Burkholderia thailandensis to physiologically relevant shifts from pH 7.0 to mildly acidic or alkaline conditions. ...

Photos from Grove Lab's post 08/21/2026

Finally - celebrating Ahmed's graduation! Thank you for the treat, Sir!

08/14/2026

Congratulations Elaine, M.Ed.

07/02/2026

Sarmin presenting her research at the GRC conference on Bacterial Cell Surfaces! LSU Department of Biological Sciences LSU College of Science

06/18/2026

Can you spot Ahmed? Attending the CSHL Course on Statistical Analysis of Genome Scale Data.

Photos from Grove Lab's post 05/21/2026

Thank you to Sarmin & Yasodha! A lovely celebration of General Exam x2!

Photos from Grove Lab's post 05/16/2026

Another proud Grove-lab moment
Congratulations Ahmed, PhD!

Photos from Grove Lab's post 05/13/2026

Congratulations Yasodha!
Passing the General Exam with flying colors!

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532 Choppin Hall
Baton Rouge, LA
70803

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